ncRNA name | VEGF siRNA |
ncRNA Category | siRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Mus musculus |
Tissues/Cell_line | mouse embryonic fibroblast cell line NIH3T3 |
Methods | siRNA transfection, semi-qPCR, ELISA |
Expression pattern | associated |
Functional description | siRNA-VEGF can be expressed across the retina and that long-term suppression of CNV is possible through the use of stable AAV2/8-mediated siRNA-VEGF expression. |
PubMed ID | 24744609 |
Year | 2014 |
Title | Adeno-associated virus type 8 vector-mediated expression of siRNA targeting vascular endothelial growth factor efficiently inhibits neovascularization in a murine choroidal neovascularization model. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.